Androgenetic alopecia (AGA) can progress in 2 types, male and female. It’s important to understand that this is a chronic genetic process that is characterized not so much by hair loss as hair thinning. The hair becomes thinner and thinner, gradually transforming from terminal hair to vellus and then stops growing altogether. This hair transformation occurs by reducing the size of the hair follicles.
With AGA, in miniaturized hair follicles, the paravermic muscle turns into adipose tissue. However, it is not entirely clear whether this atrophy is a consequence of miniaturization or, conversely, is somehow involved in the process leading to miniaturization.
Everyone knows the role of androgens in male / female pattern baldness, but also the role of hereditary factors. In fact, the term “androgenetic” is a synthesis of these two causes: androgenic and genetic.
However, beware! It is not the androgen itself that plays a key role, but the androgen receptor. The androgen receptor is a special, genetically coded protein that can bind to various androgens. Its most closely related is 5-alpha-dihydrotestosterone – the same dihydrotestosterone that is responsible for male and female baldness.
As mentioned before, despite many successes in clinical trials, the exact mechanism of hair follicle miniaturization is still not fully known. All the drugs and technologies currently used to reverse androgenetic alopecia are preventive – that is, they simply do not allow this process to develop further. Nobody has yet been able to bring the necrotic miniaturized hair follicles back to normal. Trichology allows you to prevent and enlarge the diameter of hair that is still there. Where they are gone, only surgery can help … At Hairmitage we will be able to assess how much we can help stop the process. If the process has gone too far